Figure 3.

DLS analysis of β2m oligomer sizes after incubation with Cu(II). (A) Scattering intensities as a function of radii for a Cu-β2m sample incubated for 4 d. (B) Temporal progression of β2m oligomers for the first 15 d of an incubation in the presence of Cu(II). Monomers (M), dimers (M₂), tetramers (M₄), hexamers (M₆), and dodecamers (M₁₂) are observed. The error bars represent the standard deviations from three replicate measurements, except for the dodecamers, which were not observed in all measurements. At days 13 and 15, particles with scattering radii of >100 nm were consistently measured, but these species are not included in this plot. The lines connecting the data points are not fits of the data but are provided to simplify visualization of the data.