Figure 2.

Effect of neutropenia on infection with S. dublin (a) and LD842 (b) in BALB/c.D2 (ItyR) congenic mice. Mice were infected 1 day after being treated with anti-RB6–8C5. CFU in spleen (squares) and liver (triangles) at time points after i.v. injection of bacteria. In this and subsequent figures, the spleens are cfu per organ and the livers are cfu per gram of tissue. Solid lines are neutropenic mice, and dotted lines are control mice. Each point is the geometric mean ± SD of at least four mice. All of the neutropenic mice (4/4) died by day 5, so there are no values for cfu on day 6 for this group.