Table 1.

Effect of pharmacological treatments on Kv1.1 mRNA steady-state levels

	Kv1.1/cyclophilin mRNA level, % of control
	2 h	4 h	6 h	24 h
KC1	—	—	50.2  ±  1.1***	48.0  ±  2.8***
PMA	—	—	41.7  ±  1.6***	43.4  ±  4.0***
A23187	—	—	41.3  ±  3.6***	129.2  ±  9.6***
Forskolin	54.7  ±  0.1*	47.2  ±  3.4*	38.7  ±  1.4*	22.5  ±  0.1***
1,9-dideoxyforskolin	—	—	—	93.6  ±  0.5
8-cpt-cAMP	42.6  ±  1.3*	—	17.5  ±  3.6*	9.4  ±  0.3***
Iso/IBMX	49.7  ±  0.3**	23.8  ±  0.4***	19.8  ±  0.4***	18.5  ±  2.9***
Iso	—	—	47.2  ±  0.7**	—
IBMX	—	—	58.2  ±  0.1*	—

PMA, phorbol 12-myristate 13-acetate; 8-cpt-cAMP, 8-(4-chlorphenylthio)-adenosine 3′,5′-cyclic monophosphate. ∗, P ≤ 0.05; ∗∗, P ≤ 0.005; ∗∗∗, P ≤ 0.001.