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P-gp and Fas expression as determined by flow cytometry
| Cell line | Mean fluorescence
|
|||
|---|---|---|---|---|
| P-gp | Fas | IgG control | IgM control | |
| CCRF | 7.5 | 38.8 | 5.4 | 3.9 |
| A7+ | 492.6 | 39.5 | 8.1 | 5.3 |
| 4G9 | 12.3 | 40.7 | 6.2 | 4.2 |
| 1C10 | 260.2 | 49.5 | 7.5 | 5.6 |
| 2H6 | 9.1 | 41.0 | 6.3 | 5.0 |
| 2G10 | 350.9 | 43.5 | 9.0 | 7.0 |
| K562 | 6.1 | 13.8 | 6.2 | 6.3 |
| KVIN | 166.7 | 18.0 | 7.7 | 11.7 |
CEM and K562 subclones were incubated with mAbs against P-gp (MRK-16, IgG), Fas (CH-11, IgM), or appropriate isotype control mAbs. Bound antibodies were analyzed by flow cytometry.
