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Active site surfaces in the RasQ61 mutants and in the wild type structure in complex with GppNHp (yellow). (A) Q61L; (B) Q61V; (C) Q61K; (D) Q61I (R32), (E) Q61G (PDB entry 1ZW6); (F) Wild Type (R32). Surfaces were constructed using PyMOL and colored based on atom type (N, blue; O, red; C, green). Only protein atoms were used to define the surface. Areas outlined in white define the protein/solvent interface. Wat175 represents the pre-catalytic water molecule.
