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. Author manuscript; available in PMC: 2009 Feb 28.
Published in final edited form as: Mol Cell. 2008 Feb 29;29(4):419–427. doi: 10.1016/j.molcel.2007.11.038

Figure 2. Diagram of wild type and mutant ArgRS.

Figure 2

The two AUG initiation codons for high molecular weight ArgRS (AUG1) and for free ArgRS (AUG74) are indicated, together with the nucleotide change made to inactivate each codon. The cross-hatched region represents the N-terminal hydrophobic extension that distinguishes the two forms of ArgRS and is responsible for assembly of high molecular weight ArgRS into the multisynthetase complex.