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. Author manuscript; available in PMC: 2008 Mar 24.
Published in final edited form as: Biostatistics. 2005 Apr 14;6(3):450–464. doi: 10.1093/biostatistics/kxi021

Table 3.

Summary of inferences on parameters. The left part of the table is obtained by setting αT to 1. The right part is obtained by placing a uniform prior on αT

αT = 1
 αT ~ u(0, 1)
Mean 95% PI Mean 95% PI
MSI specificity αM 0.92 (0.90, 0.94) 0.92 (0.90, 0.93)
MSI sensitivity βM 0.81 (0.73, 0.89) 0.85 (0.74, 0.96)
Mutation analysis specificity αT 1 0.97 (0.91, 1.0)
Mutation analysis sensitivity βT 0.62 (0.56, 0.67) 0.62 (0.57, 0.68)
Prevalence in high-risk group πh 0.56 (0.50, 0.63) 0.53 (0.46, 0.61)
Prevalence in low-risk group πl 0.049 (0.032, 0.071) 0.042 (0.022, 0.064)