. Author manuscript; available in PMC: 2008 Mar 24.

Published in final edited form as: Biostatistics. 2005 Apr 14;6(3):450–464. doi: 10.1093/biostatistics/kxi021

Table 4.

The data table broken down by imputed genotype. The top table is imputated under the constraint that the specificity of mutation analysis is 1, the bottom without the constraint. In each cell, the first number is the expected number of true mutation carriers of all subjects in that corresponding column in Table 1; the second number is the number of noncarriers

	High risk		Low risk
	Mut = 1	Mut = 0	Mut = 1	Mut = 0
α_T = 1
MSI = 1	279 + 0	171 + 35	42 + 0	27 + 133
MSI = 0	65 + 0	41 + 400	10 + 0	7 + 1541

α_T < 1
MSI = 1	278 + 1	168 + 38	38 + 4	24+ 136
MSI = 0	51 + 13	32 + 410	7 + 45	4 + 1500