Figure 3.

Infection of HUVECs by NY-1 is inhibited by integrin-specific antibodies. HUVECs were pretreated with 20 ng/ml–20 μg/ml of integrin-specific antibodies for 1 hr as described in Fig. 2. After primary antibody addition (1 hr, 37°C) and PBS washing, a 1/2,000 dilution of anti-rabbit or anti-mouse sera, respectively, was incubated with cells (1 hr, 37°C). Infected cells were quantitated as in Fig. 1, and results are presented as the percentage of inhibition of control infections.