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. 1998 Jun 23;95(13):7742–7747. doi: 10.1073/pnas.95.13.7742

Figure 4.

Figure 4

Effect of the GR antagonist RU38486 on the locomotor response to an intra-VTA infusion of vehicle or morphine (1 μg/μl per side). The i.c.v. administration of the GR antagonist RU38486 (100 ng/6 μl) did not modify the response to intra-VTA vehicle but reduced the response to intra-VTA morphine of about 50%. Each point represents the mean ± SEM of activity scores cumulated over 30 min. Columns show total activity scores over 3 hr. The antagonist was administered 2 hr before the infusion of morphine.