Table 1.

VZV DNA and proteins in ganglia during latency

	Percent neurons positive for VZV DNA or protein
DNA/ORF	Patient 1	Patient 2	Patient 3	Mean ± SD
DNA	11	18	10	13  ±  4.4
4	10	21	20	17  ±  6.1
62	6	10	9	8  ±  2.1
63	3	9	6	6  ±  3
21	9	23	17	16  ±  7
29	18	22	24	21  ±  3.1
10	0	0	0	0
14	0	0	0	0
67	0	0	0	0

VZV DNA was detected as previously described (9), and the proteins were detected as described in Materials and Methods. The table shows results obtained with ganglia from three seropositive patients with no clinical signs of VZV infection (latency). The results are expressed as percentage of neurons with detectable nuclear VZV DNA or cytoplasmic VZV protein. Zero indicates the absence of detectable protein. None of our antibodies reacted with VZV proteins located in the nuclei of these neurons. A total of 200 neurons were scored for each ganglion examined. The SD is provided for the mean values.