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. 2008 Mar-Apr;15(2):246–254. doi: 10.1197/jamia.M2488

Table 3.

Table 3 Overview of all Case Studies Topics and the Participants’ Background in the Three Training Challenges

  • Case Study 1

  • (TC 1)

  • The modelling of genetic regulatory networks in cancer

  • (Chemistry, Biology/BioInformatics/Chemistry, Medicine, Biology/Statistics, Physics/Computer Science)

  • Case Study 2

  • (TC 1)

  • Modelling of lipid genetic and metabolic pathways in response to infection and immune stimulation. Implication in Atherosclerosis

  • (Medicine/Genetics, Computer Science/Chemistry, Epidemiology, Biology/BioInfomatics, Chemistry/Computer Science)

  • Case Study 1

  • (TC 2)

  • Targeting EGFR signal transduction pathway by anticancer drugs

  • (Epidemiology/Computer Science, Chemistry, Computer Science, Chemistry/BioInformatics, Biology/Computer Science)

  • Case Study 2

  • (TC 2)

  • Commonalties of and differences between hormonal pathways in breast, endometrium and prostate cancer

  • (Biology/BioInformatics, Medicine/Epidemiology/BioInformatics, Physics/Computer Science, BioInformatics, Biology/Computer Science)

  • Case Study 1

  • (TC 3)

  • Kinase 1 as new target for treatment of leishmaniases

  • (Pharmaceutical BioTechnology/BioChemistry, Human Biology, Medicine/Dentistry, Computational Science Engineer, Molecular Microbiology/Informatics)

  • Case Study 2

  • (TC 3)

  • Study of the relevance of different targets for rheumatoid arthritis treatment: TNF-α and MAPK

  • (Biology, Chemistry, Medicinal Chemistry/BioInformatics, Biomedical Engineer/Telecommunications Engineer)

TC = Training Challenge.