TABLE 1.
Characteristics of isolated perfused hearts during hypoxia-reoxygenation experiments
| Factors
|
|||||
|---|---|---|---|---|---|
| Time | Group | CPP (mmHg) | Heart rate (beats/min) | LVEDP (mmHg) | LVDP (mmHg) |
| Baseline | CT | 59±3 | 284±8 | 0 | 120±6 |
| PR | 59±3 | 290±8 | 0 | 122±4 | |
| PT | 56±2 | 289±8 | 0 | 113±4 | |
| PR+PT | 64±2 | 281±6 | 0 | 126±5 | |
| 45 min of hypoxia | CT | 95±10 | 27±19 | 81±6 | 13±8 |
| PR | 88±7 | 49±25 | 80±8 | 19±9 | |
| PT | 85±6 | 25±11 | 65±6 | 29±11 | |
| PR+PT | 81±2 | 55±18 | 56±5 | 51±14 | |
| 30 min of reperfusion | CT | 86±7 | 247±8 | 31±4 | 70±5 |
| PR | 95±9 | 278±13 | 35±7 | 76±4 | |
| PT | 94±3 | 266±15 | 24±3 | 75±5 | |
| PR+PT | 104±5 | 278±16 | 17±2* | 81±6 | |
All values are expressed as means ± SEM.
*
P<0.05 versus the control (CT) group. CPP Coronary perfusion pressure; LVDP Left ventricular developed pressure; LVEDP Left ventricular end-diastolic pressure; PR Ischemic preconditioning; PT Ischemic postconditioning; PR+PT PR plus PT