TABLE 2.
Characteristics of isolated perfused hearts during H2O2 washout experiments
| Factors
|
|||||
|---|---|---|---|---|---|
| Time | Group | CPP (mmHg) | Heart rate (beats/min) | LVEDP (mmHg) | LVDP (mmHg) |
| Baseline | CT | 57±1 | 297±9 | 0 | 114±3 |
| PR | 55±2 | 298±6 | 0 | 110±3 | |
| PT | 56±3 | 268±7 | 0 | 114±3 | |
| End time of perfusion with H2O2 | CT | 86±2 | 301±10 | 50 | 28±2 |
| PR | 81±3 | 307±9 | 50 | 26±1 | |
| PT | 81±2 | 275±13 | 50 | 28±2 | |
| 30 min of washout | CT | 82±3 | 297±10 | 39±5 | 53±6 |
| PR | 77±3 | 296±8 | 36±6 | 63±7 | |
| PT | 78±4 | 264±13 | 25±4* | 74±3* | |
All values are expressed as means ± SEM.
*
P<0.05 versus the control (CT) group. CPP Coronary perfusion pressure; LVDP Left ventricular developed pressure; LVEDP Left ventricular end-diastolic pressure; PR Ischemic preconditioning; PT Ischemic postconditioning