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. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2007 Feb 2;292(6):H2854–H2866. doi: 10.1152/ajpheart.01347.2006

TABLE II.

Parameter Values of SR Ca2+ Release Model

Value
Parameter Dog Guinea-Pig Units Definition
β0 4.75 4.75 ms minimal value for βτ
Kβ 0.28 mmol/L Half-saturation constant of Δβτ,CaMK
Δβ0 1 mmol/L maximal CaMKII-dependent change for βτ
αRel κβτ κβτ mmol/L/ms amplitude coefficient of IRel,∞
KRel,∞ 1 1 mmol/L Half-saturation constant of IRel,∞
hRel 8 9 Hill coefficient of IRel,∞
hβ 10 Hill coefficient of Δβτ,CaMK
κ 0.1125 0.125 μF/μA amplitude coefficient ofαRel
KRel,τ 0.0123 0.0123 mmol/L Half-saturation constant of IRel,τ
τtr 120 120 ms time constant of Itr
γCai 0.341 1 ms Ca2+ activity coefficient
Īup,CamK 0.9 mmol/L maximal CaMKII-dependent change of Iup