Table 3. HLA-C alleles and SJS/TEN with ocular complications.
|
HLA-C alleles |
Carrier frequency |
Allele frequency |
||||||
|
SJS (n=71) |
Normal (n=113) |
p |
Odds ratio |
SJS (n=142) |
Normal (n=226) |
p |
Odds ratio |
|
| *0102 |
0.268 |
0.327 |
0.4 |
- |
0.141 |
0.168 |
0.48 |
- |
| (19/71) |
(37/113) |
(20/142) |
(38/226) |
|||||
| *0303 |
0.239 |
0.168 |
0.24 |
- |
0.12 |
0.093 |
0.41 |
- |
| (17/71) |
(19/113) |
(17/142) |
(21/226) |
|||||
| *0304 |
0.366 |
0.23 |
0.046 |
1.9 |
0.197 |
0.124 |
0.057 |
- |
| (26/71) |
(26/113) |
(28/142) |
(28/226) |
|||||
| *0401 |
0.07 |
0.115 |
0.45 |
- |
0.035 |
0.058 |
0.46 |
- |
| (5/71) |
(13/113) |
(5/142) |
(13/226) |
|||||
| *0501 |
0.014 |
0 |
0.39 |
- |
0.007 |
0 |
0.39 |
- |
| (1/71) |
(0/113) |
(1/142) |
(0/226) |
|||||
| *0602 |
0 |
0.035 |
0.16 |
- |
0 |
0.018 |
0.3 |
- |
| (0/71) |
(4/113) |
(0/142) |
(4/226) |
|||||
| *0702 |
0.211 |
0.212 |
0.99 |
- |
0.12 |
0.119 |
0.99 |
- |
| (15/71) |
(24/113) |
(17/142) |
(27/226) |
|||||
| *0704 |
0.014 |
0.018 |
1 |
- |
0.007 |
0.009 |
1 |
- |
| (1/71) |
(2/113) |
(1/142) |
(2/226) |
|||||
| *0801 |
0.099 |
0.168 |
0.28 |
- |
0.049 |
0.088 |
0.22 |
- |
| (7/71) |
(19/113) |
(7/142) |
(20/226) |
|||||
| *0803 |
0.028 |
0.053 |
0.71 |
- |
0.014 |
0.027 |
0.71 |
- |
| (2/71) |
(6/113) |
(2/142) |
(6/226) |
|||||
| *1202 |
0.127 |
0.212 |
0.17 |
- |
0.07 |
0.115 |
0.16 |
- |
| (9/71) |
(24/113) |
(10/142) |
(26/226) |
|||||
| *1402 |
0.141 |
0.097 |
0.37 |
- |
0.078 |
0.053 |
0.35 |
- |
| (10/71) |
(11/113) |
(11/142) |
(12/226) |
|||||
| *1403 |
0.225 |
0.204 |
0.72 |
- |
0.113 |
0.106 |
0.85 |
- |
| (16/71) |
(23/113) |
(16/142) |
(24/226) |
|||||
| *1502 |
0.099 |
0.044 |
0.22 |
- |
0.049 |
0.022 |
0.23 |
- |
| (7/71) | (5/113) | (7/142) | (5/226) | |||||
There was no association between HLA-C and SJS/TEN with ocular complications.