TABLE 4.

EFFECT OF NEONATAL CS EXPOSURE ON LUNG VOLUME

	Body Weight		Lung Volume		Lung Volume/Body Weight
	Mean	SD ±	Mean	SD ±	Mean	SD ±
8 wk neonatal cigarette smoke–exposed mice	19.5	2.3	0.22*	0.04	0.011†	0.001
8 wk control mice	18.5	1.6	0.25	0.03	0.014	0.002

Body weight was measured in grams. Lung volume measurements were performed using water displacement as described in Materials and Methods. Lung volume values were recorded as a change in weight (grams) with water displacement.

^*Statistical differences were found between 8-week-old mice exposed to neonatal cigarette smoke and age-matched control mice for lung volume measurements (P < 0.04).

^†Statistical differences also were found between 8-week-old mice exposed to neonatal cigarette smoke and age-matched control mice for lung volume/body weight (P < 0.002, n = 11 for mice exposed to 2 weeks of cigarette smoke and n = 12 for age-matched control mice, ± represents SD).