TABLE 5.

EFFECT OF NEONATAL CS EXPOSURE ON LUNG MORPHOMETRY

	Mean Linear Intercept (± SD)	Alveolar Number (± SD)	Alveolar Radius (± SD)
8 wk neonatal cigarette smoke–exposed mice	41.5 ± 1.3*	69.3 ± 4.4†	17.8 ± 1.0
8 wk control mice	37.4 ± 0.6	86.8 ± 6.2	15.8 ± 1.2

^*Statistical differences were found between 8-week-old mice exposed to neonatal cigarette smoke and age-matched control mice for mean linear intercept measurements (P < 0.005).

^†Statistical differences were also found between 8-week-old mice exposed to neonatal cigarette smoke and age-matched control mice for alveolar number (P < 0.007, n = 4 for mice exposed to 2 weeks of cigarette smoke and n = 3 for age-matched control mice, ± represents SD). For alveolar radius size, differences between the two groups did not quite reach statistical significance (P < 0.07).