. Author manuscript; available in PMC: 2009 Feb 1.

Published in final edited form as: Drug Discov Today. 2008 Feb 1;13(3-4):124–134. doi: 10.1016/j.drudis.2007.12.005

Table 3.

Resources for Ophthalmic Photodynamic Therapy

Component	Functions	Examples (Reference)
Delivery System	Reservoir or carrier for photosensitizer, drug, or gene	Liposome (10, 13, 14, 17)
		Polymeric micelle (3, 18, 19, 23)
	Controlled solute release
		Vectosome (25, 26)
	Targetability
		Hydrogel (28, 29)
	Biocompatibility
	Limited toxicity
Photosensitizer	React to produce highly reactive ¹O₂ in the presence of light	1^st Generation (30, 31)
		2^nd Generation (2, 37, 38)
		Quantum Dots (40−42)
Light Source	Activate photosensitizer & plasmid release	White light (2)
		Dye laser (25)
	Effective within 600−800 nm range
		Diode laser (2, 30)
Gene	Therapeutic agents	Viral vectors (5, 43)
		Non-viral vectors (5, 44, 45)