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. 2007 Oct 12;407(Pt 3):461–469. doi: 10.1042/BJ20070658

Figure 2. The induction of fetuin-B expression by CDCA and/or GW4064 is FXR-dependent.

Figure 2

HepG2 cells were transfected with either siRNA targeting FXR or negative control siRNA. At 12 h post siRNA transfection, cells were treated with either 75 μM CDCA or 1 μM GW4064 for the next 24 h. Human fetuin-B mRNA levels were then measured by real-time QPCR and normalized to cyclophilin mRNA levels. Results are expressed as a relative expression compared with DMSO in the control group; results are means±S.E.M. (n=3).