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. 2008 Jan 10;36(5):1415–1428. doi: 10.1093/nar/gkm1046

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Microarray data analysis. (A) Gene Ontology terms displaying a statistically significant over-representation in the sample-set (up- and down-regulated genes, respectively). Parameter ‘genes’ is the number of genes annotated by the corresponding term in the sample set; parameter ‘P-value’ refers to the over-representation (see Methods section for statistical details); parameter ‘ratio’ is calculated as the ratio between term frequency in the sample set versus the universe set (all microarray genes). Terms have been pruned, and then grouped according to manually determined macro-categories, identified by different colors: see the legend for the categories names; categories with similar colors are functionally related. (B) Down-regulated genes, annotated by GO terms ‘M Phase’, both ‘Cell Cycle’ and ‘Microtubule Cytoskeleton’. IDs are expressed according to NCBI Entrez Gene.