Figure 5. Dominant Negative PPARγ Causes Altered Contraction to Agonists.
The contractile response of thoracic aorta to KCl (A), PGF2α (B), 5-HT (C, D), and phenylephrine (E) was assessed. S-P467L aorta (filled circle), NT littermates (grey circle). In D, S-V290M (filled diamond), S-WT (filled square) and NT (grey triangle) was examined. *, P<0.05 transgenic vs. NT. Error bars represent SEM.