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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Free Radic Biol Med. 2007 Sep 25;44(5):768–778. doi: 10.1016/j.freeradbiomed.2007.09.011

Figure 5. Inhibitors of mitochondrial GSH transport exacerbate MQ-induced apoptosis in NCM460 cells.

Figure 5

NCM460 cells were treated for 2h with 50µM MQ or preincubated for 1h with 20mM each of the mitochondrial GSH transport inhibitors, BM and PS prior to MQ exposure. Whenever present, NAC (2mM) was added at 30min prior to MQ exposure. Cell apoptosis was determined by DAPI staining. Results are expressed as mean ± S.E. for n=3 for control, BM/PS alone, and MQ without or with BM/PS, or n=4 for BM/PS + NAC. *p< 0.05 versus control; #p< 0.05 versus MQ