Table 1.
Genes used in this study involved in heterokaryon incompatibility in N. crassa and P. anserina and in Programmed Cell Death (PCD) in S. cerevisiae. All genes are given with their presumed function and references. ID numbers for N. crassa and S. cerevisiae proteins refer to the numbers given in their respective sequencing projects, the ID numbers for the P. anserina proteins were taken from GenBank. The table is an expanded v. of the table in Glass and Kaneko (2003).
| Species | Class | Gene | Function | References | |
|---|---|---|---|---|---|
| N. crassa | |||||
| Heterokaryon incompatibility genes | |||||
| het-6OR (NCU03533.2) | allelic het-gene, TOL/HET-6/HET-E domain | Saupe 2000 | |||
| het-c (NCU3125.2) | allelic het-gene, signal peptide | Sarkar et al. 2002 | |||
| Saupe et al. 2000 | |||||
| un-24 (NCU03539.2) | allelic het-gene, ribonucleotide reductase large subunit | Saupe 2000 | |||
| Smith et al. 2000 | |||||
| Suppressor genes | |||||
| tol (NCU04453.2) | TOL/HET-6/HET-E domain | Shiu & Glass 1999 | |||
| vib-1 (NCU03725.2) | regulation of conidiation and maybe of nrAPase | Xiang & Glass 2002 | |||
| Incompatibility related genes | |||||
| ham-2 (NCU03727.2) | hyphal fusion, putative transmembrane protein | Xiang et al. 2002 | |||
| pin-c (NCU03494.2) | allelic gene with HET-domain, linked to het-c | Kaneko et al. 2006 | |||
| rnr-a (NCU07887.2) | suppresses un-24 temperature sensitive mutation, ribonucleotide reductase small subunit | Kotierk & Smith 2001 | |||
| P. anserina | |||||
| Heterokaryon incompatibility genes | |||||
| het-c2 (AAA20542) | nonallelic het-gene interacts with het-d and het-e, glycolipid transfer protein | Saupe et al. 1994 | |||
| het-d2y (AAL37301) | nonallelic het-gene against het-c2, GTP-binding, WD repeat, TOL/HET-6/HET-E domain | Espagne et al. 2002 | |||
| het-e4s (AAL37297) | nonallelic het-gene against het-c2, GTP-binding, WD repeat, TOL/HET-6/HET-E domain | Espagne et al. 2002 | |||
| het-S (AAB88771) | allelic het-gene, prion analog | Coustou et al. 1997 | |||
| Incompatibility related genes | |||||
| idi-1 (AAC24119) | induced by het-c/e and r/v incompatibility, signal peptide | Dementhon et al. 2003 | |||
| Bourges et al. 1998 | |||||
| idi-2 (AAC24120) | induced by het-r/v incompatibility, signal peptide | Bourges et al. 1998 | |||
| idi-3 (AAC24121) | induced by het-c/e and r/v incompatibility, signal peptide | Bourges et al. 1998 | |||
| idi-4 (j/b-a) | bZIP motif, putative trans-activation domain | Dementhon et al. 2004, 2005 | |||
| (AAT40415) | |||||
| idi-6 (pspA) | induced by het-c/e and r/v incompatibility, subtilisin-like serine protease | Paoletti et al. 2001 | |||
| (AAC03564) | Reichard et al. 2000 | ||||
| idi-7 (AAN41258) | ortholog of the S. cerevisiae aut7p | Pinan-Lucarre et al. 2003 | |||
| Modifier genes | |||||
| mod-A (AAC25496) | modifier of het-c/e, c/d and r/v incompatibility, SH3-binding motif | Barreau et al. 1998 | |||
| Bourges et al. 1998 | |||||
| mod-D (AAC24766) | modifier of het-c/e incompatibility, G protein α subunit | Loubradou et al. 1999 | |||
| mod-E (AAB97626) | modifier of het-r/v incompatibility, HSP90 | Loubradou et al. 1997 | |||
| S. cerevisiae | |||||
| Programmed Cell Death genes | |||||
| atp4 (YPL078C) | F0F1-ATPase | Matsuyama et al. 1998 | |||
| cdc48 (YDL126C) | cell division cycle, AAA ATPase, fusion of ER-derived vesicles | Madeo et al. 1997 | |||
| hel10 (YNL208W) | unknown | Ligr et al. 2001 | |||
| hel13 (YOR309C) | unknown | Ligr et al. 2001 | |||
| mca1/yca1 (YOR197W) | metacaspase | Madeo et al. 2002 | |||
| nsr1 (YGR159C) | rRNA processing | Ligr et al. 2001 | |||
| ppa1 (YHR026W) | vacuolar H+-ATPase | Ligr et al. 2001 | |||
| rsm23 (YGL129C) | mitochondrial small ribosomal unit | Madeo et al. 2002 | |||
| sar1 (YPL218W) | ER to Golgi transport | Ligr et al. 2001 | |||
| stm1 (YLR150W) | suppressor of pop2 and tom2 | Ligr et al. 2001 | |||
| tor1 (YJR066W) | regulation of cell death, phosphatidylinositol 3-kinase | Rohde et al. 2001 | |||
| Dementhon et al. 2003 | |||||
| Fitzgibbon et al. 2005 | |||||