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. 2008 Jan 28;9:63. doi: 10.1186/1471-2105-9-63

Table 5.

Top Scoring Phylogenetic 3'UTR Motifs Identified in 3'UTRs. Top 1% and 5% Gene Sets.

Rank Motif Genes with Motif Genes w/o Motif Genes with Motif Genes w/o Motif Fisher's exact p-value Hochberg adj p-value
Top 1% Phylo Motifs Genes Overexpressed in ER+ Tumors Genes Overexpressed in ER- Tumors

1 YACTGCCR 17 113 2 143 0.0002 0.0423
2 YYGCATGT 10 120 1 144 0.0037 1.0000
3 TGTANANAGA 12 118 3 142 0.0142 1.0000
4 TGCMNTAA 26 104 14 131 0.0168 1.0000
5 TGTGAA 51 79 37 108 0.0196 1.0000
6 TGTANNNTAG 13 117 4 141 0.0214 1.0000
7 TTTCTRNNAAA 2 128 11 134 0.0219 1.0000
8 AAGCACA 19 111 9 136 0.0273 1.0000
9 CTAKWTTT 23 107 12 133 0.0286 1.0000
10 TTTCTA 52 78 41 104 0.0423 1.0000

Top 5% Phylo Motifs

1 WGCCTTA 134 562 80 652 < 0.0001 0.0031
2 CTAKWTTT 149 547 93 639 < 0.0001 0.0032
3 TGTGAA 305 391 238 494 < 0.0001 0.0034
4 TATATTT 210 486 149 583 < 0.0001 0.0066
5 TGTANNNTAG 73 623 36 696 0.0001 0.0235
6 TGTRNNNWATT 148 548 101 631 0.0002 0.0571
7 WRCCAAAA 113 583 71 661 0.0003 0.0706
8 TGTATANW 218 478 168 564 0.0004 0.1144
9 CTGTATWW 134 562 91 641 0.0005 0.1248
10 TGTRNTTT 310 386 261 471 0.0007 0.1747