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. Author manuscript; available in PMC: 2008 Mar 26.
Published in final edited form as: J Immunother. 2004;27(3):184–190. doi: 10.1097/00002371-200405000-00002

TABLE 3.

HLA-Blocking Assay of Clones M-E10 and M-D5

Controls†
M-E10 M-D5 M-A1 LB7 LB11
Target* Plus (pg/mL IFN-γ)
No mAb 940 1009 860 484 606
Anti-HLA class I 0 1 0 336 13
Anti-HLA A2 839 765 30 446 536
Anti-HLA B/C 0 34 610 419 8
Anti-HLA class II 788 657 659 64 440
T cell alone 0 0 0 3 4
% reduction 100 97 97 87 99
*

Targets: 526 mel for M-E10 and M-A1; 1928 for M-D5; F002Rmel for LB7 and LB11.

†

Controls: M-A1 is an HLA-A2-restricted, MART-1-specific CTL clone. LB7 and LB11 are two allogeneic HLA-DR- and HLA-B/C-restricted clones, respectively.