TABLE 4.
No Recognition of Autologous Cell Lines, 1928mel and 1973mel, by Autologous HLA-A2-Restricted TIL Clones
| TIL Clones from Patient
|
|||||
|---|---|---|---|---|---|
| MB4 | M6 | MR7 | M8 | M26 | |
| Targets | (pg/mL IFN-γ) | ||||
| 938mel* | 7 | 8 | 11 | 40 | 36 |
| 624mel† | >1000 | >1000 | >1000 | >1000 | >1000 |
| 1928mel | 32 | 41 | 41 | 11 | 11 |
| 1973mel | 41 | 43 | 43 | 16 | 7 |
| Medium | 42 | 23 | 14 | 15 | 4 |
| Antigen recognition | TRP-2-6b | MART-1 | TRP-2 | NY-ESO-1 | gp100 |
HLA-A2 positive control melanoma cell line.
HLA-A2 negative control melanoma cell line.