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. 2007 Dec 6;149(3):1338–1349. doi: 10.1210/en.2007-1137

Figure 8.

Figure 8

Lymphocyte subpopulations in NOD mice treated with saline (C) or 2 μg Ex-4. Single-cell populations from spleen, thymus, and lymph nodes of NOD mice that survived until the end of experiment 2 (panels A, C, E, and G) and experiment 4 (panels B, D, F, and H) were used for flow cytometry. The number of B and T cells were examined in the spleen (panels A and B) and lymph nodes (panels C and D). The absolute number of CD4+CD25+Foxp3+ cells (Tregs) and CD4+CD25-Foxp3+ cells was determined for the thymic (panels E and F) and lymph node (panels G and H) populations (n = 5–14 mice per group for data shown in panels A, C, E, and G and n = 4–8 mice per group for data shown in panels B, D, F, and H). Values are expressed as mean ± sem. Statistical differences between treatment and control animals in lymphocyte subpopulations were calculated using Student’s t test. *, P < 0.05.