Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Mar 17;205(3):595–610. doi: 10.1084/jem.20071985

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2008, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 2. — Allelic distribution and binding scores of 178 MHC I–associated peptides eluted from EL4 cells. (A) Pie chart shows distribution of 178 MHC I–associated peptides eluted from EL4 cells. The smm, SYFPEITHI (H2D^b and H2K^b), and Rankpep (Qa2) computational models were used to link individual peptides to MHC I allelic products. (B) Logo showing the profile motif for peptides presented by H2-D^b, H2-K^b, and Qa2 molecules. Acidic (red), basic (blue), hydrophobic (black), and neutral (green) amino acids are illustrated. (C) Individual source proteins for peptides presented by H2D^b and H2K^b (n = 164) were entered in the smm binding algorithm. We assessed the predicted MHC I binding affinity of all peptides contained in individual proteins. Pie charts show the proportion of peptides eluted from EL4 cells that ranked in the top 1% (blue), top 5% (green), top 10% (yellow), or below the 90th percentile of peptides (red).