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. 2008 Mar 17;205(3):657–667. doi: 10.1084/jem.20071734

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Copyright © 2008, The Rockefeller University Press

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Figure 3. — Inflammatory cell infiltrate composition is very similar in SPARC^+/+ and SPARC^−/− mice. SPARC^+/+ and SPARC^−/− mice were injected intradermally in the back skin with 10⁷ CFU of attenuated S. typhimurium SL3261 AT 48 and 72 h later, the sites characterized by an inflammatory reaction were excised, and cells were isolated by collagenase treatment. Cells were stained with fluorescent antibodies and analyzed by flow cytometry. (A) Y axes show percentage of marker-positive cells, x axes show the analyzed markers. (B) Y axes show total numbers of marker positive cells, x axes show the analyzed markers. Error bars represent the SD of three independent mice. One of three independent experiments is shown. SPARC ^−/−, black bars; SPARC^+/+, white bars.