Table 4.
Mean (±SEM) number of c-Fos-positive cells in brain regions of mice injected with HCRT 0.3 μg or vehicle. All regions included with p<0.15. As determined by Q-value software (see Methods), regions with p<0.05 reach significance and are shown in bold.
| Brain Region | Vehicle (n) | HCRT 0.3 (n) | One-way ANOVA |
|---|---|---|---|
| AOM | 3.8±1.0 (9) | 18.0±4.5 (7) | p= 0.011# |
| AOP | 4.4±2.9 (9) | 15.9±6.6 (7) | p= 0.041# |
| FCgCx | 46.1 ±16.5 (11) | 81.4±22.8 (8) | p = 0.047# |
| LS1 | 48.1±13.0 (11) | 98.4±19.4 (8) | p = 0.039 |
| LSV1 | 4.9±15.8 (11) | 114.9±14.2 (8) | p = 0.015 |
| LSV2 | 56.8±11.6 (11) | 122.4±25.8 (8) | p = 0.039 # |
| SCN | 104.1±20.5 (10) | 157.5±11.1 (8) | p = 0.049 |
| AHA | 23.3±4.6 (10) | 37.8±3.8 (8) | p = 0.032 |
| PVA | 318.8±34.2 (9) | 429.4±33.5 (8) | p = 0.036 |
| AHP | 54.9±8.6 (11) | 116.6±18.0 (8) | p = 0.004 |
| VMH | 13.1±2.8 (10) | 32.4±7.4 (8) | p = 0.018 |
| STh | 10.9±1.6 (10) | 5.6±2.4 (8) | p = 0.040# |
| LC | 48.1±13.0 (11) | 98.4±19.4 (8) | p = 0.039 |
|
| |||
| NuAC | 34.6±6.8 (11) | 76.4±18.9 (7) | p = 0.062 # |
| NuASh | 18.2±5.2 (10) | 37.6±8.1 (7) | p = 0.051 |
| BNSTd | 27.4±4.2 (11) | 41.4±5.4 (8) | p = 0.053 |
| IL | 67.7±15.4 (11) | 114.6±21.4 (8) | p = 0.098# |
| MS/VDB | 22.2±8.5 (9) | 49.1±13.3 (7) | p = 0.097 |
| SHi | 20.2±6.6 (11) | 39.5±9.1 (8) | p = 0.095 |
| Cg Cx | 46.8±11.1 (11) | 91.3±21.9 (8) | p = 0.066 |
| LS2 | 14.3±5.9 (11) | 33.4±9.5 (8) | p = 0.052 # |
| MPA | 43.5±9.2 (11) | 70.4±8.4 (7) | p = 0.061 |
| MPOM | 63.5±12.3 (11) | 92.6±12.1 (7) | p = 0.131 |
| CA1 | 6.6±2.5 (11) | 14±4.5 (8) | p = 0.144 |
| DG | 18.455±3.4 (11) | 28.5±6.0 (8) | p = 0.136 |
| PH | 129.7±24.3 (7) | 207.7±31.6 (6) | p = 0.072 |
| APT | 15.6±6.6 (11) | 27.5±5.3 (8) | p = 0.063 # |
#
- data non-normal, analyzed with the Kruskal-Wallis One Way ANOVA on Ranks