Figure 3.

The ex vivo fall in supernatant adenosine concentration as a result of uptake into erythrocytes and uridine uptake into erythrocytes with and without dipyridamole. (a) Concentration of adenosine as measured in the supernatant up to 15 min after ex vivo addition of adenosine to whole blood that was sampled at baseline and during intra-arterial infusion of dipyridamole (n=8). (b) Uridine uptake as a function of uridine concentration as measured in blood that was collected at baseline and during intra-arterial dipyridamole infusion (n=7). V_max: 158±20 and 34±8 nmol per min per mg protein in absence and presence of dipyridamole, respectively. Data are mean±s.e.mean. V_max, maximum velocity.