Table 1.
FBF3-min and MAP3-min at baseline and after ischaemia
|
MAP3−min (mm Hg) |
FBF3-min (ml min−1 per 100 ml) |
|||
|---|---|---|---|---|
| Visit 1 (placebo) | Visit 2 (caffeine) | Visit 1 (placebo) | Visit 2 (caffeine) | |
| # | † | # | $ | |
| Base 1 | 82.3±2.3 | 81.8±3.3 | 2.5±0.5 | 2.8±0.4 |
| Base 2 | 82.6±1.8 | 83.6±3.3 | 2.4±0.5 | 3.1±0.4 |
| 2 min ischaemia | 82.3±1.6 | 84.2±3.6 | 5.6±0.7 | 6.6±0.5 |
| 5 min ischaemia | 83.4±1.6 | 84.7±3.9 | 9.7±1.3 | 10.2±0.6 |
| 13 min ischaemia | 83.8±1.7 | 83.9±3.6 | 34.5±2.1 | 35.1±2.2 |
| Base 3 | 85.1±1.6a | 86.8±3.9a | 3.0±0.6a | 3.7±0.5a |
| Dipy | 85.8±1.7a | 87.9±3.9a | 3.4±0.5a | 3.7±0.4a |
| 2 min ischaemia | 86.2±1.6 | 86.7±3.7 | 7.7±0.8 | 7.4±0.4 |
| 5 min ischaemia | 86.2±1.7 | 86.5±3.8 | 12.5±1.5 | 10.5±0.6 |
| 13 min ischaemia | 87.1±2.6 | 85.5±3.7 | 41.6±3.1 | 33.7±2.2 |
Abbreviations: Dipy, baseline during dipyridamole infusion; FBF, forearm blood flow; FBF3-min and MAP3-min, average of 3 min of reperfusion; MAP, mean arterial pressure.
Data are mean±s.e.mean.
a
P<0.05 versus base 1 and base 2; #P<0.05 for the effect of dipyridamole;
†
P>0.1 for the interaction between caffeine and dipyridamole points to both P>0.1 and P<0.01 and $P<0.01 for the interaction between caffeine and dipyridamole.