Skip to main content
. 2008 Feb 11;153(6):1296–1302. doi: 10.1038/bjp.2008.9

Figure 5.

Figure 5

Effect of anti-TNF-α, anti-IL-1α and anti-IL-1β on β-toxin-induced plasma extravasation in the dorsal skin of mice. Anti-TNF-α antibody (1 μg per site), anti-IL-1α antibody (1 μg per site), anti-IL-1β antibody (1 μg per site) antisera and control goat IgG (1 μg per site) were administered i.d. 12 h before the experiment. Mice received β-toxin (50 ng per site) or saline (0.05 ml per site), and plasma extravasation was measured 60 min after the injection of β-toxin. Values are mean±s.e.mean, n=6. *P<0.01, compared with β-toxin with control goat IgG. I.d., intradermally; IL-1α, interleukin-1α; IL-1β, interleukin-1β; TNF-α, tumour necrosis factor-α.