Table 2. Clinical variables statistically associated with Gas6.
|
Gas6 mRNA
|
||||
|---|---|---|---|---|
| Variable | <2.2 × 106 | >2.2 × 106 | P-value | |
| PRB IHC (n=30) | ||||
| Negative (⩽10%) | 10 (77%) | 3 (23%) | 0.04 | |
| Positive (>10%) | 7 (35%) | 11 (65%) | ||
| <Mean | >Mean | |||
| Lymph node metastases (n=49) | ||||
| Average (s.d.) | 4.219 (5.35) | 0.5 (1.07) | 0.0002 | |
| (s.e.m.) | (0.84) | (0.378) | ||
| <Mean | >Median | |||
| Nuclear morphology (NM) (n=38) | ||||
| NM=1 or 2 (n=7) | 4 (57%) | 3 (43%) | 0.03 | |
| NM=3 (n=31) | 28 (90.3%) | 3 (9.7%) | ||
| <Median | >Median | |||
| Age (n=49) | ||||
| ⩽50 years (n=24) | 2 (20%) | 8 (80%) | 0.04 | |
| >50 years (n=25) | 22 (56%) | 17 (44%) | ||
| Margin type (n=38) | ||||
| Infiltrating (n=19) | 13 (65%) | 7 (35%) | 0.05 | |
| Pushing (n=19) | 6 (33%) | 12 (67%) | ||
| 0 | <Mean | >Mean | ||
| Size (n=49) | ||||
| Continuous variable | ||||
| Mean (s.d.) | 54.83 (29.87) | 37.19 (18.9) | 22.33 (5.8) | 0.02 |
| NPI (n=49) | ||||
| Continuous variable | ||||
| Mean (s.d.) | 5.76 (1.35) | 5.12 (1.18) | 3.94 (0.59) | 0.03 |
IHC=immunohisto chemistry; NPI=Nottingham prognostic index; PRB=progesterone B.