Skip to main content
. 2008 Feb 19;98(6):1109–1117. doi: 10.1038/sj.bjc.6604253

Table 1. Gene expression of wild-type survivin, survivin-2B, and survivin-deltaEx3 in 134 NSCLCs according to clinical characteristics.

    Wild-type survivin
Survivin-2B
Survivin-deltaEx3
Variables n Standardised gene expression ratio P-value Standardised gene expression ratio P-value Standardised gene expression ratio P-value
Tumour status
 T1 46 1.407±0.786 0.3145 1.472±1.094 0.6335 0.922±0.614 0.3219
 T2 48 1.475±0.698   0.985±0.515   0.884±0.526  
 T3 22 1.817±0.885   1.345±0.747   1.189±0.720  
 T4 18 1.646±0.905   1.144±0.681   1.063±0.638  
               
Nodal status              
 N0 86 1.459±0.835 0.1613 1.265±0.748 0.5628 0.902±0.564 0.0781
 N1, N2, N3 48 1.660±0.707   1.175±0.914   1.096±0.673  
               
Pathological stage
 Stage I 60 1.385±0.819 0.0558 1.281±0.796 0.5626 0.833±0.512 0.0174
 Stage II, III 74 1.649±0.759   1.194±0.860   1.084±0.661  
               
Differentiation              
 Well 34 1.288±0.712 0.0383 1.318±0.832 0.4964 0.743±0.526 0.0110
 Moderately or poorly 100 1.614±0.807   1.203±0.832   1.049±0.619  
               
Histology              
 Adenocarcinoma 66 1.362±0.664 0.0181a 1.192±0.736 0.5191a 0.854±0.587 0.0377a
 Squamous cell carcinoma 65 1.690±0.892   1.285±0.923   1.075±0.616  
 Large cell carcinoma 3 1.780±0.570   0.850±0.507   1.321±0.620  
               
Total 134 1.531±0.795   1.233±0.830   0.971±0.610  

Abbreviation: NSCLCs=non-small cell lung cancers.

a

Squamous cell carcinoma vs adenocarcinoma.