Table 1. Gene expression of wild-type survivin, survivin-2B, and survivin-deltaEx3 in 134 NSCLCs according to clinical characteristics.
Wild-type survivin
|
Survivin-2B
|
Survivin-deltaEx3
|
|||||
---|---|---|---|---|---|---|---|
Variables | n | Standardised gene expression ratio | P-value | Standardised gene expression ratio | P-value | Standardised gene expression ratio | P-value |
Tumour status | |||||||
T1 | 46 | 1.407±0.786 | 0.3145 | 1.472±1.094 | 0.6335 | 0.922±0.614 | 0.3219 |
T2 | 48 | 1.475±0.698 | 0.985±0.515 | 0.884±0.526 | |||
T3 | 22 | 1.817±0.885 | 1.345±0.747 | 1.189±0.720 | |||
T4 | 18 | 1.646±0.905 | 1.144±0.681 | 1.063±0.638 | |||
Nodal status | |||||||
N0 | 86 | 1.459±0.835 | 0.1613 | 1.265±0.748 | 0.5628 | 0.902±0.564 | 0.0781 |
N1, N2, N3 | 48 | 1.660±0.707 | 1.175±0.914 | 1.096±0.673 | |||
Pathological stage | |||||||
Stage I | 60 | 1.385±0.819 | 0.0558 | 1.281±0.796 | 0.5626 | 0.833±0.512 | 0.0174 |
Stage II, III | 74 | 1.649±0.759 | 1.194±0.860 | 1.084±0.661 | |||
Differentiation | |||||||
Well | 34 | 1.288±0.712 | 0.0383 | 1.318±0.832 | 0.4964 | 0.743±0.526 | 0.0110 |
Moderately or poorly | 100 | 1.614±0.807 | 1.203±0.832 | 1.049±0.619 | |||
Histology | |||||||
Adenocarcinoma | 66 | 1.362±0.664 | 0.0181a | 1.192±0.736 | 0.5191a | 0.854±0.587 | 0.0377a |
Squamous cell carcinoma | 65 | 1.690±0.892 | 1.285±0.923 | 1.075±0.616 | |||
Large cell carcinoma | 3 | 1.780±0.570 | 0.850±0.507 | 1.321±0.620 | |||
Total | 134 | 1.531±0.795 | 1.233±0.830 | 0.971±0.610 |
Abbreviation: NSCLCs=non-small cell lung cancers.
Squamous cell carcinoma vs adenocarcinoma.