Skip to main content
. 2008 Feb 19;98(6):1109–1117. doi: 10.1038/sj.bjc.6604253

Table 2. Biological behaviours in relation to gene expressions of survivin variants and survivin protein expressions.

  n Ki-67 proliferation index Apoptotic index Growth index
Wild-type survivin
 Positive 72 57.4±22.0 P<0.0001 18.1±5.6 P<0.0001 3.47±1.68 P<0.0001
 Negative 62 36.2±28.5   23.1±7.2   1.66±1.37  
               
Survivin-2B              
 Positive 72 50.0±26.4 P=0.1776 19.8±6.9 P=0.3399 2.86±1.76 P=0.0583
 Negative 62 43.4±28.2   21.0±6.5   2.28±1.64  
               
Survivin-deltaEx3
 Positive 101 53.4±25.5 P<0.0001 20.0±6.7 P=0.1872 3.01±1.76 P<0.0001
 Negative 33 29.8±25.0   21.8±7.1   1.48±1.33  
               
Nuclear survivin
 Positive 88 52.4±26.5 P=0.0047 19.9±7.0 P=0.2662 3.02±1.88 P=0.0004
 Negative 46 38.5±26.6   21.3±6.5   1.90±1.33  
               
Cytoplasmic survivin
 Positive 98 48.3±26.9 P=0.6075 20.1±6.7 P=0.4464 2.70±1.81 P=0.4805
 Negative 36 45.6±28.7   21.1±7.2   2.45±1.74