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. 2008 Mar 18;98(6):1029–1033. doi: 10.1038/sj.bjc.6604218

Table 3. Overall survival and prognostic factor categories (log-rank test for univariate analysis and Cox regression for multivariate analysis).

      Statistical analysis
(n=212) Median (weeks) 95% CI Univariate Log Rank Multivariate Cox Reg
Albumin <35 g l−1 26 18.6–33.4 <0.0001 0.007
Normal albumin 74 54.3–95.1    
Elevated LDH 34 24.3–44.0 0.003 0.002
Normal LDH 59 41.6–77.0    
WCC >10 500 mm−3 16 5.7–26.3 <0.0001 0.439
Normal WCC 47 36.6–56.8    
HGB <12 g dl−1 31 22.4–39.0 0.0001 0.309
Normal HGB 60 37.9–82.4    
PLT >400 000 mm−3 23 8.3–37.7 0.0035 0.394
Normal PLT 47 35.8–57.4    
>2 MTS sites 30 18.3–40.8 0.0007 0.025
0–2 MTS sites 52 38.1–65.0    
Female 26 11.6–40.4 0.027 0.618
Male 54 39.7–67.5    
<65 years 38 30.1–46.2 0.0271 0.343
⩾65 years 60 25.6–94.6    
Liver MTS 25 22.7–27.0 0.0186 0.574
No liver MTS 47 36.8–56.6    
Lung MTS 36 25.3–45.6 0.0234 0.0804
No Lung MTS 54 38.5–45.8    
No Bone MTS 38 29.8–46.4 0.0004 0.425
Bone MTS 88 60.1–115    
Non-urologic tumours 26 17.8–34.8 <0.0001 0.001
Urologic tumours 98 67.6–129    
ECOG 0–1 44 34.8–54.3 0.0048 0.376
ECOG 2 17 12.6–22.8    
Monotherapy trial 38 44.9–108 0.0005 0.157
Combination trial 76 28.4–47.8