Table 2. Correlation of EDD expression with clinicopathological and gene expression variablesa.
| Variable | P-valueb |
|---|---|
| Age | 0.20 |
| FIGO Stage | 0.12 |
| Tumour grade | 0.17 |
| Surgical debulking | 0.59 |
| Menopausal status | 0.52 |
| CA125 | 0.027 |
| Adjuvant chemotherapy | |
| P only | 0.94 |
| P+C | 0.44 |
| P+T | 0.38 |
| M only | 0.97 |
| VEGF >2 vs ⩽2 | 0.80 |
| p53 >10% vs ⩽10% | 0.50 |
| p27Kip1 ⩽65% vs >65% | 0.22 |
| p21Wap/Cif1 ⩽10% vs >10% | 0.22 |
| Cyclin D1 >10% vs ⩽10% | 0.90 |
| Cyclin E >10% vs ⩽10% | 0.21 |
C=cyclophosphamide; M=melphalan; P=platinum; T=paclitaxel.
a
EDD expression was modelled as a continuous variable. Clinicopathological and gene expression variables were dichotomised as shown in Table 1, as described in the text (VEGF) and Bali et al, 2004 (cell cycle markers).
b
Bold type indicates significant P-values.