Table 3. DPB1 supertype frequency in childhood leukaemia and solid tumours compared with controls.
Leukaemia
|
Solid tumour
|
||||||||
---|---|---|---|---|---|---|---|---|---|
DPB1 supertype | % | OR | 95% CI | P | % | OR | 95% CI | P | Newborn controls % |
DP2 (GEG) | 10.3 | 1.6 | 1.2–2.0 | 0.0002* | 7.3 | 1.1 | 0.8–1.5 | 0.6 | 6.8 |
DP4 (GKG) | 59.6 | 1.1 | 0.9–1.2 | 0.38 | 60.3 | 1.1 | 0.9–1.3 | 0.3 | 58.0 |
DP6 (LED) | 6.8 | 1.3 | 1.0–1.8 | 0.04 | 6.5 | 1.3 | 0.9–1.8 | 0.2 | 5.2 |
DP3 (LKD) | 12.0 | 0.9 | 0.7–1.1 | 0.29 | 12.8 | 0.9 | 0.8–1.2 | 0.8 | 13.2 |
DP8 (GED) | 1.4 | 2.9 | 1.4–6.3 | 0.006* | 0.6 | 1.4 | 0.5–3.9 | 0.8 | 0.5 |
DP1 (GKD) | 6.9 | 0.6 | 0.5–0.7 | <10−4* | 8.6 | 0.8 | 0.6–1.1 | 0.09 | 11.1 |
Global χ2 | <10−6** | 0.04 | |||||||
Number= | 895 | 409 | 864 |
*Significant (P<0.05) after correction for six supertypes.
**Significant (P<0.05) in global χ2 (CLUMP) analysis.