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. 1998 Jun 23;95(13):7784–7788. doi: 10.1073/pnas.95.13.7784

Figure 4.

Figure 4

Pancreatic β cells secrete NGF in response to different glucose concentrations. Cells stimulated with 20 mM glucose secrete 50–180 pg/ml NGF. Cells stimulated with 5 mM glucose secrete 20–60 pg/ml NGF. NGF secretion in KCl (40 mM) + 11 mM glucose was significantly different from secretion in 5 mM glucose, but not from secretion in 20 mM glucose (50–220 pg/ml vs. 50–180 pg/ml). NGF secretion is diminished by 67% when cells are cultured with dbcAMP (5 mM) + 11 mM glucose with respect to 11 mM glucose alone. An ∗ denotes P < 0.05 with respect to 5 mM glucose; + denotes P < 0.05 with respect to 11 mM glucose (Student’s t test, n = 4).