Figure 1.

Comparison of concentrations of tyrosine hydroxylase (TH) and dopamine transporter (DAT) the caudate nucleus (CN), putamen (Pu) and ventral striatum (ventralmost part of the putamen and nucleus accumbens; VSTR) of control subjects and patients with Parkinson's disease without (PD) or with dementia (PDD). Bar graphs represent the mean±S.E. of the amount (arbitrary units) of TH (A) and DAT (B) in the striatal measured by quantitative Western blotting as described in Materials and Methods. The data were statistically analyzed separately for individual brain regions by one-way ANOVA with Group (control, PD, PDD) as main factor followed by Bonferroni/Dunn post hoc test. * - p<0.05, ** - p<0.01, * - p<0.001 to control.