FIGURE 5.

(A) Effect of the biophysical feedback on the control of the steady-state The four marginal distributions P(), obtained from 10⁶ random parameter sets in which all seven enzyme rates V_cell,Enzyme are varied, show a reduction of the probability of inviable states with < −1/6 nm⁻¹. In the absence of feedback, we fix K_a,MGS at the reference value of K_a,MGS () shown in Fig. 3 B (×). MGS is modeled to have a 19-residue α-helix (□), DGS is modeled with a 19-residue α-helix (○), both MGS and DGS are modeled with 19-residue α-helices (▵). (B) The cumulative probability that the steady state forms a bilayer () as a function of the logarithmic variation k.