Table 5.

Importance of LSCC in the paths of different subnetworks

subnetwork	cc	sp	sr	ds	dd
average path length	4.64	3.55	2.31	2.10	1.94
PERCENTPATH	87.1	69.4	72.1	57.8	54.6
PERCENTLENGTH	94.2	78.0	81.6	64.4	59.0

In each physiological subnetwork we consider the set P of pairs of the form TF-TT such that there is a chain of interactions (a path) from the TF of the pair to the TT; for p ∈ P we define ℓ_p, the length of the shortest path for this pair; moreover, Q is the subset of P such that the respective path has to go through LSCC. Then average path length = ∑_p∈Pℓ_p/|P|, PERCENTPATH = |Q|/|P|, and PERCENTPATH = ∑_p∈Qℓ_p/∑_p∈Pℓ_p.