Figure 1.

Lytic capability of C. pneumoniae. HAEC were infected or additionally treated with chloramphenicol. LDH release was analyzed in three independent experiments 24 h, 48 h and 72 hpi and mean chlamydial induced specific lysis was calculated. Mean and SD (N = 3) at 48 hpi is shown. Significant differences are indicated if p < 0.05 as calculated by students t-test. C. pneumoniae specific lysis of HAEC is dose dependent and reaches a plateau at 20 IFU/cell. In contrast chloramphenicol treated infected HAEC were not lysed.