Table 2.
Fifteen Different Combinations of Templates Used in Exploring the Effect of PID.
| Combination | Template 1 | Template 2 | Template 3 | Template 4 |
| 1 | ✓ | |||
| 2 | ✓ | |||
| 3 | ✓ | |||
| 4 | ✓ | |||
| 5 | ✓ | ✓ | ||
| 6 | ✓ | ✓ | ||
| 7 | ✓ | ✓ | ||
| 8 | · | ✓ | ✓ | |
| 9 | ✓ | ✓ | ||
| 10 | ✓ | ✓ | ||
| 11 | ✓ | ✓ | ✓ | |
| 12 | ✓ | ✓ | ✓ | |
| 13 | ✓ | ✓ | ✓ | |
| 14 | ✓ | ✓ | ✓ | |
| 15 | ✓ | ✓ | ✓ | ✓ |
To explore the effect of the number and diversity of templates on RAPPER building using the Standard mode of conformer generation, fifteen combinations as shown in the table where used. Template 1 was closest by PID to the target with Template 4 the most remote.