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. Author manuscript; available in PMC: 2009 Apr 9.
Published in final edited form as: Behav Brain Res. 2007 Dec 7;188(2):380–390. doi: 10.1016/j.bbr.2007.11.022

Figure 4. Open field activity of Lsamp−/− mice.

Figure 4

The distance traveled, measured in centimeters (cm), by Lsamp−/− mice and their Lsamp+/+ littermates is displayed in 10 minute bins (a&b). Both female (a) and male (b) Lsamp−/− mice exhibit hyperactivity when exposed to the novel arena. Female Lsamp−/− mice habituate to normal levels of activity within 20 minutes of being placed in the arena, but male Lsamp−/− mice remain hyperactive for the duration of the 30 minute test. (n=13−15/group). Examination of activity in the open field for a 60 minute period (c) revealed that the null mice return to normal levels of activity by the second half of the test period. The increase in distance traveled by male Lsamp−/− mice during the second 10 min bin (20) was not significant at p = 0.06 (n=7 WT, n=8 Lsamp−/−).*p<0.05