Table 1.
Indian medicinal plants with antidiabetic and related beneficial properties
Plant Name | Ayurvedic/common name/herbal formulation | Antidiabetic and other beneficial effects in traditional medicine | References |
---|---|---|---|
Annona squamosa | Sugar apple | Hypoglycemic and antihyperglycemic activities of ethanolic leaf-extract, Increased plasma insulin level | [61–63] |
Artemisia pallens | Davana | Hypoglycemic, increases peripheral glucose utilization or inhibits glucose reabsorption | [64] |
Areca catechu | Supari | Hypoglycemic | [65] |
Beta vulgaris | Chukkander | Increases glucose tolerance in OGTT | [66] |
Boerhavia diffusa | punarnava | Increase in hexokinase activity,decrease in glucose-6-phosphatase and fructose bis-phosphatase activity, increase plasma insulin level, antioxidant | [67–69] |
Bombax ceiba | Semul | Hypoglycemic | [70] |
Butea monosperma | palasa | Antihyperglycemic | [71] |
Camellia sinensis | Tea | Anti-hyperglycemic activity, antioxidant | [72, 73] |
Capparis decidua | Karir or Pinju | Hypoglycemic, antioxidant, hypolipidaemic | [35] |
Caesalpinia bonducella | Sagarghota, Fevernut | Hypoglycemic, insulin secretagogue, hypolipidemic | [74, 31, 32] |
Coccinia indica | Bimb or Kanturi | Hypoglycemic | [36] |
Emblica officinalis | Amla, Dhatriphala, a constituent of herbal formulation, “Triphala” | Decreases lipid peroxidation, antioxidant, hypoglycemic | [75–77] |
Eugenia uniflora | Pitanga | Hypoglycemic, inhibits lipase activity | [78] |
Enicostema littorale | krimihrita | Increase hexokinase activity, Decrease glucose 6-phosphatase and fructose 1,6 bisphosphatase activity. Dose dependent hypoglycemic activity | [79, 80] |
Ficus bengalenesis | Bur | Hypoglycemic, antioxidant | [81] |
Gymnema sylvestre | Gudmar or Merasingi | Anti-hyperglycemic effect, hypolipidemic | [82, 83] |
Hemidesmus indicus | Anantamul | Anti snake venom activity, anti-inflammatory | [84] |
Hibiscus rosa-sinesis | Gudhal or Jasson | Initiates insulin release from pancreatic beta cells | [85] |
Ipomoea batatas | Sakkargand | Reduces insulin resistance | [86] |
Momordica cymbalaria | Kadavanchi | Hypoglycemic, hypolipidemic | [87, 88] |
Murraya koenigii | Curry patta | Hypoglycemic, increases glycogenesis and decreases gluconeogenesis and glycogenolysis | [89] |
Musa sapientum | Banana | Antihyperglycemic, antioxidant | [90–92]. |
Phaseolus vulgaris | Hulga, white kidney bean | Hypoglycemic, hypolipidemic, inhibit alpha amylase activity, antioxidant. Altered level of insulin receptor and GLUT-4 mRNA in skeletal muscle | [93–95] |
Punica granatum | Anar | Antioxidant, anti-hyperglycemic effect | [96] |
Salacia reticulata | Vairi | inhibitotory activity against sucrase, α-glucosidase inhibitor | [97] |
Scoparia dulcis | Sweet broomweed | Insulin-secretagogue activity, antihyperlipidemic, hypoglycemic, antioxidant | [98–100] |
Swertia chirayita | Chirata | Stimulates insulin release from islets | [101] |
Syzygium alternifolium | Shahajire | Hypoglycemic and antihyperglycemic | [102] |
Terminalia belerica | Behada, a constituent of “Triphala” | Antibacterial, hypoglycemic | [103] |
Terminalia chebula | Hirda | Antibacterial, hypoglycemic | [103] |
Tinospora crispa | Anti-hyperglycemic, stimulates insulin release from islets | [104] | |
Vinca rosea | Sadabahar | Anti-hyperglycemic | [105] |
Withania somnifera | Ashvagandha, winter cherry | Hypoglycemic, diuretic and hypocholesterolemic | [106] |