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. Author manuscript; available in PMC: 2009 Feb 13.
Published in final edited form as: Mol Cell Endocrinol. 2007 Dec 8;283(1-2):114–126. doi: 10.1016/j.mce.2007.11.031

Fig. 4.

Fig. 4

Ability of STAMP ± TIF2 to alter PR and GR induction properties in CV-1 cells. Triplicate wells of CV-1 cells were transfected with 100 ng GREtkLUC and 20 ng Renilla null luciferase reporters plus 0.3 ng PR (A), or 6 ng GR (B), ± 20 ng TIF2 and ± 160 ng Flag/STAMP. The cells were induced and analyzed, and the results plotted, as in Fig. 1. (C) Fold changes in PR and GR induction parameters by STAMP and TIF2. The average fold-increase in each parameter from 4-5 experiments like Figs. 4A & B were determined as follows: for EC50s, fold increase = [EC50]receptor/[EC50] receptor +factor; for partial agonist activity and Vmax (or total agonist activity), fold increase = activityreceptor+factor/activityreceptor).