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. Author manuscript; available in PMC: 2009 Feb 13.
Published in final edited form as: Mol Cell Endocrinol. 2007 Dec 8;283(1-2):114–126. doi: 10.1016/j.mce.2007.11.031

Table 2.

Modulation of induction parameters with added Ubc9 in 1470.2 cells

Fold Increase in
Fold Decrease in
Receptor
Fold Induction
Vmax
Partial Agonist Activity
EC50
PR (0.3ng) 0.84 ± 0.08
(0.11)
1.85 ± 0.15
(0.0012)
1.28 ± 0.05
(0.0016)
2.58 ± 0.37
(0.0055)
PR (10 ng) 0.54 ± 0.06
(0.0014)
1.47 ± 0.22
(0.10)
0.95 ± 0.07
(0.51)
3.07 ± 0.64
(0.032)
GR (endog.) 1.14 ± 0.08
(0.19)
2.74 ± 0.74
(0.10)
0.56 ± 0.18
(0.087)
1.15 ± 0.05
(0.051)

The average values listed are from N independent experiments similar to those of Fig. 3 but now in 1470.2 cells. The experiments were performed and analyzed as in Table 1 with the indicated amounts of transfected PR plasmid or endogenous GR (n = 7 for 0.3 ng PR, = 5 for 10 ng PR, and = 4 for GR). P values for statistical significance are in parentheses.